Gja1 Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comGja1 Polyclonal Antibody for Rat(Rattus norvegicus)

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Gja1 (Gene name),

Gap junction alpha-1 protein (Protein name ), CXA1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Gja1(Cxn-43);

Protein name:

Gap junction alpha-1 protein;

Alternative:

Gap junction 43 kDa heart protein;Connexin-43(Cx43);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

A connexon is composed of a hexamer of connexins. Interacts with SGSM3. Interacts with KIAA1432/CIP150. Interacts with CNST (By similarity). Interacts (via C-terminus) with TJP1. Interacts (via C-terminus) with SRC (via SH3 domain).

Function:

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Subcellular Location:

Cell membrane Multi-pass membrane protein Cell junction gap junction

Protein Attributes:

Sequence length:

382

Sequence:

50:

100:

150:

200:

250:

300:

350:

382:

HELQPLAIVD | QRPSSRASSR | ASSRPRPDDL | EI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P08050

UniGene:

Rn.10346

Pfam:

PF00029

KEGG:

rno:24392

SMR:

P08050

Uniprot:

P08050

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ELISA Kit for Rat Gap junction alpha-1 protein

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E2241r

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96T

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ELISA Kit for Rat Gap junction alpha-1 protein

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E2241b

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96T

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ELISA Kit for Rat Gap junction alpha-1 protein

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E2241p

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ELISA Kit for Rat Gap junction alpha-1 protein

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E2241h

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96T

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ELISA Kit for Rat Gap junction alpha-1 protein

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E2241c

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96T

ELISA Kit for Rat Gap junction alpha-1 protein

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ELISA Kit for Rat Gap junction alpha-1 protein

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E2241d

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ELISA Kit for Rat Gap junction alpha-1 protein

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E2241m

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96T

CLIA Kit for Rat Gap junction alpha-1 protein

Cat.:

U2241r

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96T

CLIA Kit for Rat Gap junction alpha-1 protein

Cat.:

U2241c

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96T

CLIA Kit for Rat Gap junction alpha-1 protein

Cat.:

U2241h

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Packing:

96T

CLIA Kit for Rat Gap junction alpha-1 protein

Cat.:

U2241b

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96T

CLIA Kit for Rat Gap junction alpha-1 protein

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CLIA Kit for Rat Gap junction alpha-1 protein

Cat.:

U2241p

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Packing:

96T

CLIA Kit for Rat Gap junction alpha-1 protein

Cat.:

U2241d

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96T

CLIA Kit for Rat Gap junction alpha-1 protein

Cat.:

U2241m

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96T

Polyclonal Antibody for Rat Gap junction alpha-1 protein

Cat.:

P2241Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat Gap junction alpha-1 protein

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P2241Rb-m

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Polyclonal Antibody for Rat Gap junction alpha-1 protein

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P2241Rb-h

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40ug/0.2ml

Monoclonal Antibody for Rat Gap junction alpha-1 protein

Protein for Rat Gap junction alpha-1 protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Connexin43: a protein from rat heart homologous to a gap junction protein from liver."
Beyer E.C. , Paul D.L. , Goodenough D.A.
J. Cell Biol.105:2621-2629(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Molecular cloning of a rat uterine gap junction protein and analysis of gene expression during gestation."
Lang L.M. , Beyer E.C. , Schwartz A.L. , Gitlin J.D.
Am. J. Physiol.260:E787-E793(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Uterus.
3.

Ma L.X. , Peng Y.W.
Submitted (2003-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Heart.
5.

"The Mr 28,000 gap junction proteins from rat heart and liver are different but related."
Nicholson B.J. , Gros D.B. , Kent S.B.H. , Hood L.E. , Revel J.-P.
J. Biol. Chem.260:6514-6517(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-33
tissue: Heart.
6.

"Affinity purification of a rat-brain junctional protein, connexin 43."
Dupont E. , el Aoumari A. , Fromaget C. , Briand J.-C. , Gros D.
Eur. J. Biochem.200:263-270(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-16
tissue: Brain.
7.

"Connexon integrity is maintained by non-covalent bonds: intramolecular disulfide bonds link the extracellular domains in rat connexin-43."
John S.A. , Revel J.-P.
Biochem. Biophys. Res. Commun.178:1312-1318(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS
8.

"Membrane topology and quaternary structure of cardiac gap junction ion channels."
Yeager M. , Gilula N.B.
J. Mol. Biol.223:929-948(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TOPOLOGY
9.

"Identification and functional analysis of novel phosphorylation sites in Cx43 in rat primary granulosa cells."
Yogo K. , Ogawa T. , Akiyama M. , Ishida N. , Takeya T.
FEBS Lett.531:132-136(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-365; SER-368; SER-369 AND SER-373
10.

"NMR structure note: UBA domain of CIP75."
Kieken F. , Spagnol G. , Su V. , Lau A.F. , Sorgen P.L.
J. Biomol. NMR46:245-250(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH UBQLN4
11.

"Involvement of urinary bladder Connexin43 and the circadian clock in coordination of diurnal micturition rhythm."
Negoro H. , Kanematsu A. , Doi M. , Suadicani S.O. , Matsuo M. , Imamura M. , Okinami T. , Nishikawa N. , Oura T. , Matsui S. , Seo K. , Tainaka M. , Urabe S. , Kiyokage E. , Todo T. , Okamura H. , Tabata Y. , Ogawa O.
Nat. Commun.3:809-809(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
12.

"Structural changes in the carboxyl terminus of the gap junction protein connexin43 indicates signaling between binding domains for c-Src and zonula occludens-1."
Sorgen P.L. , Duffy H.S. , Sahoo P. , Coombs W. , Delmar M. , Spray D.C.
J. Biol. Chem.279:54695-54701(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 255-381;INTERACTION WITH TJP1 AND SRC
13.

"Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites."
Chen J. , Pan L. , Wei Z. , Zhao Y. , Zhang M.
EMBO J.27:2113-2123(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 374-382 IN COMPLEX WITH TJP1;SUBCELLULAR LOCATION;INTERACTION WITH TJP1

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